Sal-Tropine

DESCRIPTION:

Self-administered oral tablet medication designed to decrease the amount of saliva flow.

Active Ingredient: 0.4mg Atropine Sulfate, USP (Oral Use Only)

Inactive Ingredients: corn starch, lactose, magnesium stearate, sucrose, and talc.

CLINICAL PHARMACOLOGY:

The most important and relevant therapeutic action is to decrease the activity of smooth muscles and glands controlled by postganglionic cholinergic nerves. These glands include the salivary glands of the mouth. The result is drying of the mouth.

INDICATIONS AND USAGE:

SAL-TROPINE is indicated to reduce the flow of saliva and is endorsed with the ADA Seal of Acceptance.

CONTRAINDICATIONS:

Do not use in patients with Glaucoma; adhesions (synechiae) between the iris and lens of the eye; asthma

PRECAUTIONS:

General – If you wear contact lens, they should be removed and not replace until normal tear production has been re-established. Doses of 0.5 to 1 mg of atropine are mildly stimulating to the central nervous system. When used in therapeutic doses, atropine can cause dryness of the mouth. This effect is additive when the product is administered with other drugs that can cause dryness of the mouth. This medication should be administered and monitored by a parent, guardian, or other responsible adult knowledgeable about this drug.

Drug Interactions - Since atropine sulfate slows gastric emptying and gastrointestinal motility, it may interfere with the absorption of other medications. The potential of atropine to cause mouth dryness may be increased if it is given with other drugs that have anticholinergic action (tricyclic antidepressants, antipsychotics, some antihistamines, and antiparkinsonism drugs).

Usage in Pregnancy and nursing mothers- Caution should be exercised when atropine sulfate is administered to a nursing or pregnant woman. We do not endorse this medication during those circumstances unless approved and monitored by a physician.

ADVERSE REACTIONS AND OVERDOSING:

Individual tolerance varies greatly, but these doses are likely to produce the following effects: 0.5 mg - Slight dryness of nose and mouth; bradycardia. 1 mg - Greater dryness of nose and mouth with thirst; slowing, then acceleration of heart; slight mydriasis. 2 mg - Very dry mouth; tachycardia with palpitations; mydriasis, slight blurring of near vision; flushed, dry skin. 5 mg - Increase in above symptoms plus disturbance of speech; difficulty in swallowing; headache; hot, dry skin; restlessness with asthenia.

To obtain up-to-date information about the treatment of overdose contact your certified Regional Poison Control Center.

DOSAGE AND ADMINISTRATION:

This medication should not be given to children under 65 lbs. The medication can be swallowed in tablet form or crushed and dissolved in milk or apple juice. It is best taken on an empty stomach. The effects of Sal-Tropine last approximately two hours. Children under 75 lbs are given one tablet, between 75 and 150 lbs two tablet are administered and individuals over 150 lbs take three tablets.

This medication is taken one hour before the scheduled appointment. Successful bonding (gluing) of braces is very dependent on following these instructions.